2025 Lexus Es 350 Hybrid Mpg. The base lexus es 250 can get up to 28 mpg combined, while the v6 is still relatively efficient with a combined fuel rating of up to 26 mpg. See our expert review on the 2025 lexus es hybrid and where it ranks among other luxury midsize cars.
As you’d expect, the es300h hybrid is even more frugal, achieving ratings of 43/44 mpg. Detailed specs and features for the 2025 lexus es 350 including dimensions, horsepower, engine, capacity, fuel economy, transmission, engine type, cylinders, drivetrain and more.